Phenergan caused death

Neuroleptic Malnant Syndrome. NMS information. Patient

He was not in any pain or physical discomfort during that time.

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Nausea and vomiting are mediated primarily by visceral stimulation through dopamine and serotonin, by vestibular and central nervous system causes through histamine and acetylcholine, and by chemoreceptor trger zone stimulation through dopamine and serotonin. Antihistamines and anticholinergic agents are most effective in patients with nausea resulting from vestibular and central nervous system causes.

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RACGP - Anaphylaxis

your doctor at once if you later develop symptoms throughout your body, such as: severe pain, burning, swelling, numbness, cold feeling, severe irritation, skin changes, or discoloration in your fingers or toes.

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On April 25, 2006 the FDA issued a drug safety alert about promethazine hydrocoride, warning doctors and parents that drugs containing promethazine hydrocoride (HCl) should not be given to children younger than two years of age, and they should use care in giving those drugs to children older than two years.

Phenergan caused death:

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